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DPO-1

Product Name
DPO-1
CAS No.
43077-30-1
Chemical Name
DPO-1
Synonyms
DPO-1;DOP-1 (Diphenyl phosphine oxide-1);(+)-Neomenthyl diphenylphosphine oxide;inhibit,DPO1,Inhibitor,DPO 1,Potassium Channel,DPO-1,KcsA;(1S,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl]diphenyl-phosphine oxide;Phosphine oxide, [(1S,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]diphenyl-;[1S-(1α,2α,5β)]-[5-Methyl-2-(1-methylethyl)cyclohexyl]diphenylphosphineoxide
CBNumber
CB3850927
Molecular Formula
C22H29OP
Formula Weight
340.44
MOL File
43077-30-1.mol
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DPO-1 Property

storage temp. 
Store at +4°C
solubility 
DMSO: soluble2mg/mL, clear (warmed)
form 
needles
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D7443
Product name
DPO-1
Purity
needles, >97% (NMR)
Packaging
25mg
Price
$853
Updated
2023/06/20
Cayman Chemical
Product number
29688
Product name
DPO-1
Packaging
1mg
Price
$38
Updated
2024/03/01
Cayman Chemical
Product number
29688
Product name
DPO-1
Packaging
10mg
Price
$227
Updated
2024/03/01
Cayman Chemical
Product number
29688
Product name
DPO-1
Packaging
5mg
Price
$142
Updated
2024/03/01
Tocris
Product number
2533
Product name
DPO-1
Purity
≥99%(HPLC)
Packaging
10
Price
$173
Updated
2021/12/16
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DPO-1 Chemical Properties,Usage,Production

Definition

ChEBI: [[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene is a monoterpenoid.

Biological Activity

Blocker of I Kur ultrarapid delayed rectifier potassium current and K V 1.5 channels (IC 50 = 0.31 μ M for rK V 1.5). Displays selectivity for inhibition of I Kur over I to (8-fold), I K1 , I Kr and I Ks (20-fold) in native myocytes and selectivity for rat recombinant K V 1.5 over K V 3.1 (~ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia.

storage

Store at +4°C

DPO-1 Preparation Products And Raw materials

Raw materials

Preparation Products

43077-30-1, DPO-1Related Search:


  • DPO-1
  • [1S-(1α,2α,5β)]-[5-Methyl-2-(1-methylethyl)cyclohexyl]diphenylphosphineoxide
  • (+)-Neomenthyl diphenylphosphine oxide
  • (1S,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl]diphenyl-phosphine oxide
  • DOP-1 (Diphenyl phosphine oxide-1)
  • Phosphine oxide, [(1S,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]diphenyl-
  • inhibit,DPO1,Inhibitor,DPO 1,Potassium Channel,DPO-1,KcsA
  • 43077-30-1
  • C22H29OP